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Neurosci Biobehav Rev 29 : 649674

For example, in diabetes patients, dysregulation of SLC7 transporters and imbalances in amino acid metabolism may exacerbate hyperglycemia

Hyperuricemia, a condition where theres too much uric acid in your body, is considered to be the cause of gout

From the perspective of animal experiments, in ApoE / mice expressing human cholesteryl ester transfer protein (hCETP), TMAO derived from L-carnitine levels inversely correlated with aortic lesion size in both the aortic root and thoracic aorta ( The Molecular Mechanism of TMAO Aggravating Coronary Atherosclerosis Vascular Dysfunction: TMAO Promotes Oxidative Stress and Inflammation in Endothelial Cells Vascular dysfunction is an important risk factor for atherosclerotic heart disease (44)