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demonstrated that in dendritic cells (DCs), LPS-induced glycolysis is repurposed to replenish citrate, an intermediate metabolite in the TCA cycle that is depleted for the de novo synthesis of fatty acids ( 2 ( de novo lipogenesis is important for phagocytosis as it requires ongoing lipid synthesis in the ER for membrane expansion, such that Ms can surround and capture targeted pathogens for internalization ( de novo lipogenesis, an anabolic process that is NADPH-dependent, in regulating the inflammatory response of myeloid cells

Another well-known option is milk thistle , which contains an active compound called silymarin, famed for its liver-protective qualities

The polyvinylidene difluoride membranes were incubated with primary antibodies overnight at 4C against the following proteins: CPT1a (15 1841-AP) was purchased from Proteintech

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