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The authors also searched the ClinicalTrials.gov ( and the International Clinical Trials Registry Platform ( to ensure that the search was comprehensive and to minimize publication bias

The good news is that any side effects tend to be mild and temporary, with some people experiencing no side effects at all

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Furthermore, NADPH is required for many anabolic pathways such as nitric oxide and fatty acid synthesis, however, NADPH consumption in the aldose reductase pathway under diabetic conditions causes a harmful effect on the biosynthesis process of these molecules in the retina (Thakur et al., 2021)