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Biomass Bioenergy 44, 168181

110 Treatment with 1,500 mg curcumin per day for 12 weeks was also shown to upregulate expression of a PPAR- activator molecule and improve markers of oxidative stress more than placebo in a controlled trial in 72 women with PCOS

De JongHJIKlungelOHVan DijkLVandebrielRJLeufkensHGMVan Der LaanJWet al

While there are obstacles in reaching targeted tissue delivery and reducing off-target effects, strategies involving nanoparticles and small-molecule inhibitors are actively being investigated [97, 98]