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Dec 2022;37(12):2443-2455

Zinc interferes with coppers absorption, but taking too much zinc can even cause a copper deficiency

Although GHR abundance in the liver in diabetic rats is reduced, GHR expression in kidneys was shown to be evenly increased, suggesting tissue-specific expression of GHR [202]

Acknowledgments We thank the UK Biobank study, and the summary statistics data of UKB can be download from Neale lab ( and other GWAS summary-level data, which have been downloaded from We also thank all the reviewers and editors for their useful suggestions for improving this study