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Studies have confirmed the involvement of astrocytes and pericytes in the deposition of basal lamina during angiogenesis (23, 30) and the developmental localization and polarization of ATP-binding transporters on endothelial cells (31)

doi: 10.1167/iovs.14-15167 131 RoySKimD

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In summary, advancing the field of human neuroprotection demands a multidimensional recalibration, spanning conceptual clarity, more representative preclinical models, validated biomarkers, and refined clinical endpoints