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4,5 GM-CSF is produced by both hematopoietic (eg, T cells, B cells, macrophages, monocytes) and some viscerosomatic cells (type II alveolar epithelial cells, endothelial cells, fibroblasts) and can activate cells through the dimeric GM-CSF receptor expressed primarily on monocytes and macrophages but also on dendritic cells and other cells of the innate immune system (Figure 2A)

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To extend their viability, consider freezing aliquots of the solution

In patients with endometriosis, progesterone resistance is observed, possibly related to a decrease in PRB levels [86], which tends to inactivate progesterone target genes, leading to inflammation and deficient estrogen metabolism [87]