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Glutaminase 1 inhibition reduces glycolysis and ameliorates lupus-like disease in Mrl/Lpr mice and experimental autoimmune encephalomyelitis

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Allergan USA

A second cohort of mice including WT, RAMP1 KO, RAMP3 KO, and RAMP1/3 KO genotypes confirmed that both RAMP1 and RAMP3 are individually essential for a full cagrilintide-induced neuronal activation response