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Description

Moreover, HO-3867 led to an increase in ROS in NSCLC, which dependshe accessibility of iron (98)

95%CI=1.94-3.60) and previous CAD (HR=7.85

MYC mediates PHGDH activation, which enhances GSC self-renewal by regulating redox homeostasis, promoting on-carbon metabolism and facilitating the DNA damage response via SSP activation, thereby driving GSC malignant progression and radioresistance in GBM (64)