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doi: 10.1021/tx00026a013

Cigarette smoke affects the eye mainly through ischemic or oxidative mechanisms

97, 98 Indeed, the RhoA/ROCK pathway has been shown to be involved in the formation of atherosclerotic lesions, vasoconstriction and myocardial hypertrophy and to be activated in patients with hypertension and in patients with coronary artery disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Cavalcante G.C., Schaan A.P., Cabral G.F., Santana-da-Silva M.N., Pinto P., Vidal A.F., Ribeiro-dos-Santos