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In hepatocellular carcinoma models, this approach produced high levels of ONOO inside mitochondria, causing irreversible damage to the ETC, inhibiting ATP production, and triggering cancer cell death, which significantly reduced tumor volume (134)

10.1002/glia.20919 Summary Keywords CuZn superoxide dismutase, oxidative stress, muscarinic M1 receptor, transductional mechanisms, secretion Citation Mondola P, Damiano S, Sasso A and Santillo M (2016) The Cu, Zn Superoxide Dismutase: Not Only a Dismutase Enzyme

If an SCH application is approved, under current policy, the effective date of the SCH classification is the date the MAC receives the complete application

After incubation with horseradish-peroxidase-conjugated secondary antibodies, signals were detected by Western Lightning Plus enhanced chemiluminescence Substrate (PerkinElmer, NEL103E001EA)