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As a demonstration of this, cultured rat hippocampal neuronal cells were protected from oxidative stress with uric acid [38], and administration of uric acid 24 hours prior to middle artery occlusion also attenuated brain injury induced by acute ischemia in rats [38]
There are also conditions where IV therapy is often still possible, but only after consultation with a physician to adjust formulation, volume, or infusion rate: Heart or circulation issues , such as controlled congestive heart failure, uncontrolled high blood pressure, or a history of blood clots Kidney conditions , including chronic kidney disease, reduced kidney function, or patients currently on dialysis Electrolyte imbalances , such as elevated potassium, sodium, or calcium levels Prescription medications that may interact with IV fluids, vitamins, or minerals Pregnancy and breastfeeding also fall into this category
Kendalls tau values and the p -values for rejection of H 0 : tau = 0, were thus computed for all pairs consisting of one purine metabolite and one monoamine metabolite within each of the three datasets
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