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Description

Mice null for Fbxo40 have increased levels of IRS1 and demonstrate enhanced body and muscle size during the growth phase associated with elevated IGF1 levels. Moreover, IGF-1 LR3 also helps with muscle repair via improving the proliferative capacity of muscle satellite cells (MSCs)

doi: 10.3390/cancers13050986 109 OhtaASitkovskyM

In vivo photothermal and antitumor experiments confirmed that the material can generate large amounts of heat and ROS, leading to apoptosis and tumor-growth restriction