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Following an acute administration of EtOH (5 g/kg, i.p.), KO animals exhibited 30% and 50% less EtOH and AA accumulation in circulation, respectively, suggesting an increased capacity for liver EtOH and AA metabolism in KO mice

He is national leader for Sweden for 2 ongoing stroke trials and local PI for the StrokeCLOSE study

Mood changes irritability and mood fluctuation are most prominent when pronounced peaks and troughs occur with infrequent dosing

In the same study, mutated TACSTD2 (encoding Trop2) was detected in another patient with acquired resistance to SG, which led to reduced antibody binding due to an abnormal subcellular localization of Trop2