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Disruption of these regulatory mechanisms elevates labile iron pools, potentiating Fenton reactions and ferroptosis

The optimal dosage, timing, and duration of melatonin supplementation remain the foci of ongoing research

When the body detects these pathogens, the immune system launches a massive defensive response, releasing pro-inflammatory cytokines like IL-6 and TNF- in what is sometimes called a "cytokine storm." While this inflammatory response is necessary to destroy the virus, it comes at a steep metabolic cost