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Till date, systemic skin whitening agents do not have much scientific evidence regarding their use and strict laws should be enforced to ban the use of these agents until well conducted randomized controlled trials are available ensuring the safety and efficacy of these agents

Sections were washed in PBS three times for 5 min each and were incubated with secondary antibody for 45 min

As predicted, ITGA2 gene mutation blocked organoid growth in collagen I, even in the presence of scTS2/16