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When NAFLD was stratified by NFS, subjects with advanced liver fibrosis exhibited a higher prevalence of diastolic dysfunction (49.0%, 50.7%, 61.8%

Digestive Diseases and Sciences 46 ( 11): 23472352

Leaky gut may also stem from systemic inflammation, where cytokines like interleukin (IL)1, IL-6, tumor necrosis factor (TNF)-, and interferon (IFN)- disrupt gut permeability and promote bacterial translocation by weakening tight junctions [21]