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GLXI isomerizes the hemithioacetal (HTA) formed by the spontaneous reaction between GSH and MG, into S-D-lactoylglutathione

Three main hypotheses were proposed to explain how riboflavin deficiency can lead to low parasitaemia: haemolysis, inhibition of reticulocytosis, and oxidative stress

Hyperthyroidism: some nodules can cause excess thyroid hormone production, leading to hyperthyroidism 5

While they act via identical mechanisms, AOD9604 is often preferred in oral administration studies due to its resistance to digestive enzymes, whereas standard 176-191 requires parenteral administration in research settings