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Furthermore, Western blot results also indicated that the supernatant of tumor cells treated with NP4 promoted TRPM2 protein expression in macrophages (Fig

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Consequently, AML is associated with a decrease in the expression of TJ proteins (claudin-1 and ZO-1) with a resultant increase in the translocation of LPS into the systemic circulation to promote inflammatory responses that favor the progression of the disease [110]

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