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Furthermore, histone modifications are closely linked to the function of leukemia stem cells, which are often the primary source of chemotherapy resistance

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Ibuprofen, on the other hand, is primarily processed and eliminated by the kidneys

Evolving Therapeutics in Multiple Myeloma Highly effective treatments are available in early-line settings of multiple myeloma management, such as proteasome inhibitors, immunomodulatory drugs (IMiDs), corticosteroids, and multiple drug combinations, including anti-CD38 antibodies, but treatment options for progressive disease following initial lines of therapy have historically been limited