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doi: 10.1016/j.biortech.2021.126294 230 ZhangX

However, after extensive lobbying by ALS patient advocacy groups and a promise from the company that it would consider withdrawing the drug if the larger phase 3 trial failed to confirm benefits, the advisory committee changed its mind and voted in favor of approval, Fernandez Lynch said

FRCs from the spleen or lymph nodes were isolated by enzymatic digestion as described previously 55

This is the case for GPCRs that following phosphorylation by G-protein coupled receptor kinases (GRKs) bind to their specific endocytic adaptor, -arrestin