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From Days 3 to 8, the medium was switched to Knockout DMEM, 20% Knockout Serum Replacer, beta-mercaptoethanol (BME, 100 M), 1% Glutamax, non-essential amino acids, and 1% DMSO

Specificity protein 1 (SP1) is a zinc finger transcription factor that mediates transcriptional regulation by binding to conserved promoter elements ( Selenophosphate synthetase 2 (SEPHS2) is a key enzyme in selenocysteine biosynthesis that regulates selenium availability for selenoprotein synthesis ( Although Methionine sulfoxide reductase B1 (MSRB1) was identified as a Se-ASRG, SHAP analyses and internal validation both demonstrated that other variables contributed far less to model discrimination than SP1 and SEPHS2

4 Relationship between ERS and ferroptosis: a potential new direction for the treatment of RA Studies have found that there is a shared pathway between ferroptosis and ERS, both of which are involved in cell survival processes

Wilson disease is a genetic disorder that is fatal unless detected and treated before serious illness from copper poisoning develops