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Several cellular processes are involved in the pathogenesis of AIH, including liver metabolism, mitochondrial oxidative stress and dysfunction, sterile inflammation, endoplasmic reticulum stress, autophagy, and microcirculation dysfunction

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Pyroglutamic acid, isovaleric acid, hippuric acid, 3-methyl-2-oxovaleric acid, creatinine, and threonine were significantly decreased post-seizure, while 2-oxoisocaproic acid was elevated