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The aftermath of radiation, particularly the intracerebral hemorrhage resulting from vascular rupture and blood infiltration into brain tissue, is deeply intertwined with ferroptosis [176]

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The National Cancer Institute conducted chemoinformatics analysis of 60 cell lines and showed a negative correlation between xCT expression levels and sensitivity to compounds associated with GSH-mediated resistance, which indicated that xCT expression induces chemoresistance via GSH-mediated ROS detoxification activity (82)