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miRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis

A review article

Nuclear factor-B The nuclear factor-B (NF-B) is an important inducible transcription factor playing a key role in processes of the immune and inflammatory responses, cellular adhesion, differentiation, proliferation, and apoptosis (Bonizzi and Karin 2004)

ROS can activate the NF-B pathway by promoting the degradation of IBs, allowing NF-B to translocate into the nucleus and initiate gene transcription ( Figure 3 ) (97)