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Additionally, hypertensive patients exposed to high altitudes demonstrated increased -diversity (inter-individual microbial compositional variation) and a higher abundance of Verrucomicrobia and Akkermansia (Zhu et al., 2020)

Similarly, intravenous administration of RvE1 before ischemia markedly decreased infarct size and prevented apoptosis through the phosphorylation of Akt and extracellular signal-regulated kinase 1/2 (ERK1/2) [107]