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The logic: cagrilintide adds amylin satiety, so the same hunger control can sometimes be reached with a lower retatrutide dose, which may reduce dysesthesia and GI side effects

Some authors suggest the application of different guidelines, however sometimes based on those recommended by ICH

Long term prescription of medications such as the following are likely to increase the cause of, or exacerbate the risk of B12 deficiency - the proton pump inhibitors (esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole), famotidine, ranitidine, metformin, glibenclamide, gliclazide, glimepiride, glipizide, sodium valproate, gabapentin, doxycycline, some oral contraceptives