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Studies using various modalities, including pre- and post-whole-cell patch clamping techniques in the calyx of Held, have demonstrated that TSG, unlike RES, primarily promotes NMDA-mediated EPSC via the PKC cascade [133]

To confirm the phenotype changes were driven by OGDHc inhibition, we also treated cells with DM-2OG, mimicking impaired 2-OG metabolism by the OGDHc, and found that, similarly to ML226, DM-2OG increased the CCR7 high CD45RO high population, with a corresponding decrease in the CCR7 low CD45RO high population (Fig

FT576 comprises an anti-BCMA CAR, a high-affinity non-cleavable CD16, CD38 knockdown and IL-15/IL-15 receptor and has proved competent for ADCC against MM cells

NRS: 10)