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By targeting both, medications like bimekizumab may offer greater suppression of inflammation, which may translate to improved clinical outcomes for some patients, compared with blocking IL-17A alone. Its about achieving a more complete blockage of the inflammatory signals behind psoriasis, says Lawrence Green, MD, a clinical professor of dermatology at the George Washington University School of Medicine in Washington, DC

Stress axis Both touch the stress/HPA response

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The Nrf2/ARE pathway is a well-characterized transcriptional regulatory system associated with glutathione-related biochemical processes