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(2021) used CRISPR/Cas9 to establish transgenic zebrafish lines that express mutated NF1 , Rb1 or TP53 under GFAP promoter and showed that various combinations of NF1 , TP53 , and/or Rb1 mutations can induce gliomas of different grades and phenotypes (108)

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5.2 Neurotransmitter and neuroendocrine regulation Periodontitis-related oral dysbiosis can disrupt the gut microbiota via multiple pathways, contributing to depression through neurotransmitter and neuroendocrine mechanisms

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H&E (G1003), Alcian blue (G1027), and Prussian blue staining kit (G1029) were provided by Servicebio

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Inhibition of group I metabotropic glutamate receptors reverses autistic-like phenotypes caused by deficiency of the translation repressor eif4e binding protein 2

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