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It may, in fact, be the signal that every other intervention is ultimately downstream of

Cao HY, Lian JN, Lin ZS, Zhu ZW, Wang H,Wang HY

2.3 Lipid peroxidation metabolism Iron can exacerbate the accumulation of lipid peroxides by catalyzing Fenton reaction, which in turn disrupts the intracellular redox balance, leading to an attack on biomolecules and ultimately culminating in ferroptosis