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Hum Reprod Update 5:172178 Sambandan TG, Rha C, Kadir AA, Aminudim N, Saad JM, inventors

We typically start with vagus nerve exercises like deep breathing, gargling, humming and singing, mindfulness & relaxation techniques like meditation, yoga and HRV training and optimizing sleep & circadian rhythms by having a consistent bedtime, focussing on morning sunlight exposure and more

The acellular fraction of BALF was obtained through double centrifugation, and the supernatant was used for further analysis

Even though DOX cannot cross the bloodbrain barrier (BBB), it can cause substantial neurotoxicity with neuronal and synaptic loss, prompting cognitive deficits in the brain [39, 42] In the current work, DOX-induced oxidative stress was proved by higher levels of NOX4 and MDA, accompanied by loss of antioxidant defense mechanisms shown as lower GSH and SOD activities