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31,32 Adverse effects associated with IV acetylcysteine include anaphylactoid reactions, including rash, pruritus, angioedema, bronchospasm, tachycardia, and hyper-tension

As the oxidative burden on the mitochondria is lifted, these organelles can begin to shift away from inefficient anaerobic glycolysis (which produces the brain-fog-inducing lactate) and back toward efficient aerobic ATP production