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Gastroenterology 138:15661573 Chavarria L, Alonso J, Rovira A, Cordoba J (2011) Neuroimaging in acute liver failure

It promotes extracellular matrix remodeling, reduces oxidative stress markers, and has demonstrated the ability to inhibit fibrosis in organs like the liver and lungs

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Mechanisms investigated Metabolic-pathway research converges on a small set of enzymatic and receptor targets, and these compounds map onto different ones they are not interchangeable: NNMT inhibition (5-Amino-1MQ): studied as a small-molecule inhibitor of nicotinamide N-methyltransferase, an enzyme implicated in cellular NAD/SAM metabolism