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Review of the midbrain ascending arousal network nuclei and implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM)

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Some of these substances have direct cytotoxic effects, and some others, such as fungal derivative alpha amanitin, induce apoptosis in tumor cells [203]

Emerging data suggests that co-activation of both CTR and AMYRs may confer greater efficacy in metabolic control than selective activation of AMYRs 13