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Another challenge is developing effective delivery methods for these metabolites, as they must be able to cross the blood-brain barrier to exert their therapeutic effects

A lack of vitamin B12 can lead to high levels of homocysteine in the blood which can damage the lining of the arteries and may also make the blood clot more easily, which can increase the risk of blood vessel blockages and contribute to cholesterol plaque build-up, increasing the risk of heart disease and stroke (Chiu et al., 2020)

Unless stated otherwise, the maximum normalized fluorescence was detected between the middle and end of the exponential growth phase of the culture and for the controls (i.e., empty vector or supplemented water) in the stationary phase

D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease