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The gut microbiota, a complex community of microorganisms that inhabits the intestine, varies with diet, age, and environment, and influences normal physiology and susceptibility to disease through its metabolic activities and host interactions [8]

The traditional way of diagnosing has been with a serum B12 blood test, however many sufferers of a B12 deficiency may not have anaemia, or have a serum B12 blood level within an abnormally low range in accordance to the normal ranges set

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It is especially interesting as a treatment for osteoarthritis, as it has shown better results than cortisone and hyaluronic acid injections for early-to-moderate osteoarthritis symptoms