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Continuous variables were reported as mean [standard deviation (SD)] or median [interquartile range (IQR)], whereas categorical parameters were described by counts and percentages

All animal work was performed in accordance with Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines and regulations

A physical examination may reveal unsuspected diagnoses, such as Peyronies disease (PD), pre-malignant or malignant genital lesions, prostatic enlargement or irregularity/nodularity, or signs and symptoms suggestive of hypogonadism (see Table 3.3: Specific symptoms associated with LOH)

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