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Castaldi G'14 Carlo R

The FDA has approved several interleukin inhibitors for psoriasis treatment: Methotrexate was originally used to treat cancer but has been used to treat severe psoriasis for more than 50 years

Consequently, elucidating the molecular circuitry linking Kla to macrophage immunobiology presents compelling opportunities for developing targeted antitumor strategies

In this line, the composition of the lower respiratory and nasopharyngeal tract, as well as the lungs, is affected by intestinal bacteria that are transported through micro-aspiration and bacterial metabolites circulating in the blood (90)