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Cancer-associated cachexia (CAC) was blocked in PNPLA2-deficient mice and to a lesser extent in HSL-deficient mice, demonstrating that lipolysis is essential for CAC (214)

Although this seems attractive, it is not positive, because even in the early stages (which can be prolonged), there may be no hematological symptoms and standard conventional tests may come back normal without megaloblastic anemia, but we will have very serious problems later on, as we will not be free from other types of symptoms that appear later and are uncertain

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It is one of the few compounds with direct influence on the sirtuins, proteins that regulate cellular health and lifespan