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Key Takeaways Key Takeaways Cortisone shots are anti-inflammatory steroid injections used to alleviate joint pain

Researchers have linked this to increased metabolic rate at the cellular level, driven by the downstream effects of NNMT inhibition on how fat cells process and expend energy

Although most studies have focused on bacterial changes such as increased Streptococcus and Veillonella and decreased Faecalibacterium 63,64,65,66 , fungal involvement is supported by clinical observations of severe fungal infections in PSC patients 67,68 and serological evidence such as elevated ASCA in PSC populations 69

PMID 11390785