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Severino R, Ferrari G, Vu KD, Dons F, Salmieri S, Lacroix M

Indeed, emphysema patients have significantly lower BMI compared to those with bronchitis, primarily due to reduced lean mass, fat mass, and bone mineral content

This metabolic pathway is often hijacked by oncogenic drivers such as RAS and MYC, which enhance CHKA expression to meet the demands of rapid proliferation and membrane biogenesis (Kortlever et al., 2017)