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SKU: 53496372577
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& Holmes, S

Drug Interactions Thiazolidinediones are related to the metabolism of the cytochrome P450 enzyme, CYP2C8

The resulting downregulation of JMJD3 leads to suppressed EDNRB expression and compensatory upregulation of EDNRA, promoting endothelin-mediated vasoconstriction, ERK pathway activation, and vascular remodelingall key features of hypertension [55,56,57]