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And while all sex hormones ping-pong during the menopausal transition defined as the years just before periods cease the drop in estrogen, in particular, sets off a wave of low-grade inflammation that can lead to body-wide complaints

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Acknowledgements We thank Drs Henderson and Fowler for assistance with a cryostat used for sectioning tumors, Janet Derten for assisting with the MetaMorph software, Charlie Linch for assisting with analytical flow cytometry, and Tito Woodburn, Heather Hall and Heather Davidson for assisting with cell culture, STRs and mycoplasma testing

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