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Inositol is used to treat conditions such as diabetic nerve pain, panic disorder, insomnia, depression, schizophrenia, Alzheimers disease, ADHD, autism, and psoriasis, and to promote hair growth

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In vitro, co-culture of GMSCs encapsulated in the 3D-collagen hydrogel with macrophages remarkably increased the secretion of IL-10, an anti-inflammatory cytokine characteristic of pro-regenerative (M2) macrophages, but robustly reduced LPS-stimulated secretion of TNF-1 and IL-1, two cytokines characteristic of pro-inflammatory (M1) macrophages

The primary mechanism involves direct upregulation of vascular endothelial growth factor (VEGF) and VEGFR2 receptor expression a process documented across more than 40 individual published studies