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Withanolides (WS) may work by interacting with mediators of the inflammatory cell signaling pathway such as NF-B, signaling kinases, HSP90, Nrf2, and the inflammasome complex, although the exact processes underlying their anti-inflammatory effects are still poorly understood

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One-way or 2-way ANOVA followed by Tukeys multiple-comparison test were performed where appropriate to detect significance between genotypes (see also Supplemental Table 2)