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Structural properties of EGCG-induced, nontoxic Alzheimers disease A oligomers

10.1002/glia.22679 103 KatoH.KurosakiR.OkiC.ArakiT

ROS, which include superoxide, nitric oxide, hydroxyl radical, hydrogen peroxide, and peroxynitrite, can be generated from various sources including the electron transport chain or activated immune cells

found that the downregulation of CD44 led to a decrease in -catenin expression, thereby inducing leukemia cell cycle to arrest in the G0/G1 phase, where gene transcription is blocked, and cell proliferation is inhibited (101)