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There is also the mitochondrial superoxide dismutase or SOD B in human tissues (Beckman et al., 1973), that is similar to the prokaryotes MnSOD but it has four sub-unities instead of two, and it has a molecular weight of about 80.000, having also a manganese atom per sub-unit

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Impaired transmembrane fatty acid (FA) transport mediated by carnitine palmitoyltransferase 1/2 (CPT1/2) in damaged TECs, coupled with downregulation or loss of activity in key transcription factors peroxisome proliferator-activated receptor- (PPAR-) and mitochondrial biogenesis regulator estrogen-related receptor (ESRRA), diminishes cellular energy supply

1,2 While inorganic nitrate is highly bioavailable (close to 100% absorption), betalains show low but measurable bioavailability (0.30.9%), with high inter-individual variability