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In colorectal cancer patients, co-treatment with Manuka honey (UMF 15+) and 5-fluorouracil (5-FU) increased intratumoral drug concentration by 62%, attributed to inhibition of efflux transporters such as P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) ( 4.7 Radioprotective effects and DNA repair Honey has shown radioprotective effects based on its ability to enhance DNA repair mechanisms and reduce oxidative damage in irradiated tissues

It's better to use a gentler product regularly than a harsh one sporadically

Organic acids are a group of carbon-based compounds that exhibit acidic properties, most commonly due to the presence of carboxylic acid groups (COOH)

In particular, controversial views have been expressed on the role of bioactivation of OTA and the relevance of OTA-derived DNA adducts (Manderville 2005