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Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology

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Another paper experimentally activated the GABA A receptor via injection of muscimol into the insula/S2, which reversed hyperactivity in the insula/S2 during cold-stimulation as measured by fMRI and reduced CIPN symptoms in oxaliplatin-treated monkeys (Nagasaka et al., 2017)